Gestational diabetes mellitus (GDM) is a heterogeneous multivariate pregnancy disease with complicated pathological mechanisms. In addition to inflammatory reaction, insulin resistance (IR) and abnormality of lipid and glucose metabolism, GDM also involves DNA methylation and oxidative stress signal transduction that affect cardiac function.
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The epidemic of obesity is now recognised as one of the most important public health problems facing the world today. Adult obesity is more common globally than under-nutrition.
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COVID-19 is a world-wide emergency with the first cases reported in December 2019 and more than 696,000 deaths and 18,000,000 cases of SARS-CoV-2 infection have been reported globally as of August 5th (WHO).
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