Proteins of the platelet-derived growth factor (PDGF) family are heat-steady, positively charged proteins which are engendered by osteoblasts, platelets and monocytes/macrophages. The PDGF family consists of four structurally related single polypeptide units that constitute five functional homo- or hetero-dimers: PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC, and PDGF-DD.
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