The “exercise hormone”, is not a fake news. It's in our blood and helps us lose weight. Its name is irisin and was discovered in 2012 in mice.
Irisin is secreted by muscle, increases with exercise, and mediates certain favorable effects of physical activity.
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Uromodulin - also known as Tamm-Horsfall protein - is exclusively produced in the thick ascending limb of loop of Henle in the kidneys and is the most abundant protein in the urine of healthy people but is also found in blood.
Vitamin D is sometimes called the “sunshine vitamin” because it’s produced in your skin in response to sunlight. It’s a fat-soluble vitamin and has several important functions. Perhaps the most vital roles are regulating the absorption of calcium and phosphorus, and facilitating normal immune system function.