Uromodulin - also known as Tamm-Horsfall protein - is exclusively produced in the thick ascending limb of loop of Henle in the kidneys and is the most abundant protein in the urine of healthy people but is also found in blood.
Allegedly nothing, but both share some common features including insulin resistance, abnormal insulin production, healthy cells languishing from lack of energy and a microbiome in poor condition. And there's even more.
Insulin is a peptide hormone produced by beta cells of the pancreatic islets. It lowers blood sugar levels and its secretion is controlled by the level of glucose in the blood. When the glucose level is high, the beta cells secrete insulin into the blood; when glucose levels are low, secretion of insulin is inhibited.
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