Type
Competitive ELISA
Description
The BioVendor Mouse/Rat Progesterone ELISA is a competitive immunoassay for the quantitative measurement of progesterone in rat and mouse serum or plasma. For research use only. Not for use in diagnostic procedures.
Applications
Serum, Plasma
Sample Requirements
10 µl/well
Shipping
On blue ice packs. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Curve
Calibration Range
0.4–100 ng/ml
Limit of Detection
0.156 ng/ml
Features
- RUO
- calibration range 0.4-100 ng/ml
- limit of detection 0.156 ng/ml
Research topic
Steroid hormones, Animal studies
Summary
Progesterone (4-pregnene-3, 20-dione) is a C21 steroid hormone containing a keto-group (at C-3) and a double bond between C-4 and C-5. Like other steroids, it is synthesized from cholesterol via a series of enzyme-mediated steps (1). Progesterone is a female sex hormone of primary importance in ovulation, fertility and menopause. It is particularly important in preparing the endometrium for the implantation of the blastocyte and in maintaining pregnancy (2). The rate of progesterone secretion may be affected by the degree of progestational activity of the uterus and the level of circulating LH (3). Analyses suggest that progesterone acts as an anti-glucocorticoid in rat adipose tissue in vivo, attenuating the glucocorticoid effect on adipose tissue metabolism (4). Furthermore it could be demonstrated that progesterone alone may be a valuable agent for management of postmenopausal osteoporosis (5).
In female rodents, the determination of progesterone is a useful marker in evaluating and monitoring the state of the reproductive functions and pregnancy as well.
Instructions for Use (RUO)
Instructions for Use (RUO)
Safety Information (RUO)
MSDS (RUO)
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