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Monocyte Chemotactic Protein-1 Mouse ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:MCP-1, CCL2, C-C motif chemokine 2, MCAF
  • Species:Mouse
Cat. No. Size Price


96 wells (1 kit) $694,28
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Cell culture supernatant

Sample Requirements

50 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

15.6–1000 pg/ml

Limit of Detection

2.2 pg/ml

Intra-assay (Within-Run)

CV = 6.2%

Inter-assay (Run-to-Run)

CV = 5.6%

Spiking Recovery

98,00%

Dilution Linearity

97,00%

Summary

Research topic

Cytokines and chemokines and related molecules, Energy metabolism and body weight regulation, Animal studies

Summary

Monocyte chemotactic protein-1 (MCP-1) is a member of the C-C family of chemokines. Chemokines are mediators that share the capacity to induce directional migration of leukocytes. MCP-1 is a chemoattractant for many cell types such as monocytes, neutrophils, hepatic stellate cells, granulocytes and T lymphocytes. MCP-1 is believed to play a role in a variety of pathological conditions, including inflammatory and immune reactions, atherosclerosis and neoplasia. Monocyte Chemotactic Protein-1 (MCP-1) is also known as Monocyte Chemotactic Activating Factor (MCAF) or CCL2.

Product References (2)

References

  • Mazur-Bialy AI. Superiority of the Non-Glycosylated Form Over the Glycosylated Form of Irisin in the Attenuation of Adipocytic Meta-Inflammation: A Potential Factor in the Fight Against Insulin Resistance. Biomolecules. 2019 Aug 21;9(9):394. doi: 10.3390/biom9090394. PubMed PMID: 31438646. PubMed CentralPMCID: PMC6770638. See more on PubMed
  • Moyon S, Dubessy AL, Aigrot MS, Trotter M, Huang JK, Dauphinot L, Potier MC, Kerninon C, Melik Parsadaniantz S, Franklin RJ, Lubetzki C. Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration. J Neurosci. 2015 Jan 7;35(1):4-20. doi: 10.1523/JNEUROSCI.0849-14.2015. PubMed PMID: 25568099. PubMed CentralPMCID: PMC6605244. See more on PubMed
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