Human Pancreatic Elastase ELISA

Features

• European Union: for in vitro diagnostic use
• rest of the world: for research use only!
• The kit is intended for the quantitative determination of Pancreatic Elastase in stool.
• Assay format is 96 wells
• Components of the kit are provided ready to use or concentrated

Research topic

Diabetology - Other Relevant Products

Summary

The pancreatic elastase belongs to the class of serine proteases and has a molecular weight of 26 kDa. It is a digestive enzyme that is produced in the pancreas of all vertebrates. The pancreatic elastase is produced in the pancreas as an inactive zymogen (proelastase) and activated in the small intestine by cleavage with trypsin. The elastase is excreted unmodified in the stool. The stool concentration of pancreatic elastase provides information about the performance of the pancreas.

Indications:

• Diagnosis / exclusion of exocrine pancreatic insufficiency on the occurence of unclear diarrhea, constipation, steatorrhea, flatulence, weight loss, epigastric pain and food intolerance
• Monitoring of exocrine pancreatic function in cystic fibrosis, diabetes mellitus or chronic pancreatitis

The ImmuChrom complete pancreatic elastase kit allows an easy, rapid and precise quantitative determination of pancreatic elastase in biological samples. The kit includes all reagents ready to use, except the washing buffer.