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Human Fibrinogen-like Protein 1 ELISA

  • Regulatory status:RUO
  • Type:Sandwich ELISA, Biotin-labelled antibody
  • Other names:FGL1, HP-041, Hepassocin, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, Liver fibrinogen-related protein 1, LFIRE-1, HFREP1
  • Species:Human
Cat. No. Size Price


RAG027R 96 wells (1 kit) $664
PubMed Product Details
Technical Data

Type

Sandwich ELISA, Biotin-labelled antibody

Applications

Serum, Plasma, Cell culture supernatant

Sample Requirements

1µl/well

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Range

7.8 - 500 pg/ml

Limit of Detection

2 pg/ml

Intra-assay (Within-Run)

n = 4
CV = 3.7%

Inter-assay (Run-to-Run)

n = 5
CV = 4.8%

Spiking Recovery

92 - 107%

Dilution Linearity

90 - 108%

Summary

Features

It is intended for research use only

The total assay time is less than 4 hours

The kit measures Fibrinogen-like Protein 1 in serum, plasma and cell cuture supernatant

Assay format is 96 wells

Components of the kit are provided ready to use, concentrated or dried

Research topic

Energy metabolism and body weight regulation, Oncology, Reproduction

Summary

FGL-1 (Fibrinogen-like protein 1, also called Hepatocyte-derived fibrinogen-related protein 1, HFREP-1 or Hepassocin) was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript enriched in regenerating liver. Under physiological conditions, FGL-1 is a liver secreted factor and contributes to its mitogenic and metabolic functions, but it has also been shown to be expressed at lower levels in brown adipose tissue in the setting of liver injury. FGL-1 was shown to be associated with polycystic ovary syndrome, obesity or insulin resistance.

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