Type
Sandwich ELISA
Applications
Serum, Urine, Plasma
Sample Requirements
1 µl/well
Shipping
Shipped on blue ice packs. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, all components are stable until the expiration date (see label on the box).
Calibration Range
1.25 - 40 ng/ml
Limit of Detection
0.4 ng/ml
Intra-assay (Within-Run)
n = 8
CV = 5.5%
Inter-assay (Run-to-Run)
n = 8
CV = 8.0%
Spiking Recovery
108.3%
Dilution Linearity
91.3%
Features
It is intended for research use only
The total assay time is less than 3.5 hours
The kit measures beta 2-microglobulin
Assay format is 96 wells
Quality Controls are human serum based
Standard is a recombinant protein
Components of the kit are provided ready to use, concentrated or dried
Research topic
Oncology, Renal disease
Summary
Urinary excretion of Beta 2-microglobulin (beta 2M) is a widely used test of renal proximal tubular function. Proximal tubular dysfunction leads to an increased urinary concentration.
The serum level of beta 2-microglobulin is determined by the glomerular filtration rate and the rate of synthesis. Increased production, with raised serum levels, is sometimes observed in malignancy, mainly at an advanced state.
A strong correlation between lupus nephritis (LN), disease activity, and serum beta 2-microglobulin (b2MG) was observed. Serum b2MG level can be used as a valuable predictor for LN, clinical disease activity, and damage score.
Instructions for Use (RUO)
Instructions for Use (RUO)
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