GRO-ß/MIP-2 (Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAß), CXCL2, MIP-2, GRO2)

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Re­combinant rat GRO-β/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids including the ‘ELR’ motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.