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Glucagon-Like Peptide-2 Human ELISA

  • Regulatory status:RUO
  • Type:Competitive ELISA, Immobilized antibody
  • Other names:GLP-2
  • Species:Human
Cat. No. Size Price


YK141 96 wells (1 kit) $780,2
PubMed Product Details
Technical Data

Cat # changed from RSCYK141R to YK141

Type

Competitive ELISA, Immobilized antibody

Applications

Serum, Plasma-EDTA, Plasma-Heparin, Plasma-Citrate

Sample Requirements

25 µl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.412–100 ng/ml

Intra-assay (Within-Run)

Human plasma - CV(%) 3.7 - 4.8 Human serum - CV(%) 3.0 - 5.5

Inter-assay (Run-to-Run)

Human plasma - CV(%) 13.0 - 16.4 Human serum - CV(%) 14.3 - 17.5

Spiking Recovery

Human plasma 1 - 89,4 % Human plasma 2 - 86,1 % Human serum 1 - 95,0 % Human serum 2 - 82,6 %

Summary

Research topic

Diabetology - Other Relevant Products

Summary

Proglucagon gene is expressed in both pancreatic A cell and intestinal L cell. Tissue-specific posttranslational processing of proglucagon by prohormone convertase produces different proglucagon derived peptides (PGDPs) in both pancreas and intestine. The most notable pancreatic PGDP is glucagon, whereas intestinal L cell produces several structurally related peptides, including glucagon-like peptide 1 (GLP-1) and 2 (GLP-2), as well as glicentin and oxyntomodulin which contain glucagon sequence in their molecules. Among PGDPs, GLP-2 has been found to show intestinal epithelial proliferation.

Product References (3)

References

  • Drucker DJ, Erlich P, Asa SL, Brubaker PL. Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7911-6. doi: 10.1073/pnas.93.15.7911. PubMed PMID: 8755576. PubMed CentralPMCID: PMC38848. See more on PubMed
  • Philippe J. Structure and pancreatic expression of the insulin and glucagon genes. Endocr Rev. 1991 Aug;12(3):252-71. doi: 10.1210/edrv-12-3-252. PubMed PMID: 1935821. See more on PubMed
  • Mojsov S, Heinrich G, Wilson IB, Ravazzola M, Orci L, Habener JF. Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J Biol Chem. 1986 Sep 5;261(25):11880-9. PubMed PMID: 3528148. See more on PubMed
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