| Cat. No. | Size |
Price |
|
|---|---|---|---|
| Discount F2300 | 3x 110 ml | $1306,26 |
Cat # changed from RBCF2300 to F2300
Colorimetric assay
Cell culture and/or animal studies, Tissue extract, Cell
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
Store the kit at RT or 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Extracellular matrix, Animal studies
Elastin is a key extracellular matrix protein that is critical to the elasticity and resilience of many vertebrate tissues including large arteries, lung, ligament, tendon, skin, and elastic cartilage. Tropoelastin associates with multiple tropoelastin molecules during the major phase of elastogenesis through coacervation, where this process is directed by the precise patterning of mostly alternating hydrophobic and hydrophilic sequences that dictate intermolecular alignment. Massively crosslinked arrays of tropoelastin (typically in association with microfibrils) contribute to tissue structural integrity and biomechanics through persistent flexibility, allowing for repeated stretch and relaxation cycles that critically depend on hydrated environments. Elastin sequences interact with multiple proteins found in or colocalized with microfibrils, and bind to elastogenic cell surface receptors. Knowledge of the major stages in elastin assembly has facilitated the construction of in vitro models of elastogenesis, leading to the identification of precise molecular regions that are critical to elastin-based protein interactions.