Cyclophilin H (Peptidyl-prolyl cis-trans isomerase H, PPIase H, Rotamase H, Small nuclear ribonucleoprotein particle-specific cyclophilin H, CypH, U-snRNP-associated cyclophilin SnuCyp-20, USA-CYP)

Cyclophilins promote protein folding. Cyclophilin H enables the cis-trans isomerization of proline imidic peptide bonds. It takes part in pre-mRNA splicing and assembly of the U4/U5/U6 tri-snRNP complex in the spliceosome.