CINC-1 (Cytokine-Induced Neutrophil Chemoatractant)

CINC-1 (cytokine-induced neutrophil chemoattractant) is refined from supernatant of NRK-52E cultivation, which normal rat kidney cell type. There are some kinds in CINC, each as CINC-1, CINC-2α, CINC-2β, and CINC-3. Latterly CINC-1 was confirmed as same as IL-8. CINC-1 is peptide of molecular weight of 7845, and it is a factor to promote migration of neutrophil. Since CINC-1 has proved that it induces release of cellular enzyme, it is also noted that it involves to inflammation.