Type
Immunocapture enzyme activity assay
Applications
Serum, Plasma-EDTA
Sample Requirements
100 µl/well
Shipping
Shipped on blue ice packs. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Range
0.5 - 10 U/L
Limit of Detection
< 0.5 U/L
Intra-assay (Within-Run)
n = 21
CV = 9.0%
Inter-assay (Run-to-Run)
n = 11
CV = 7.7%
Spiking Recovery
100.9%
Dilution Linearity
up to 1:5
Features
Ror research use only!
Derived exclusively from bone-resorbing osteoclasts
Low diurnal variation
No dietary influence
No accumulation into the circulation in renal or hepatic failure
Research topic
Bone and cartilage metabolism
Summary
For the quantitative determination of the active isoform 5b of tartrate-resistant acid phosphatase (TRAcP). The BoneTRAP® (TRAcP 5b) ELISA assay is a specific method to detect TRAcP 5b activity freshly liberated from osteoclasts. It is intended for use as an indicator of bone resorption and can be used as an aid in monitoring bone resorption changes in post-menopausal women and individuals diagnosed with osteoporosis undergoing anti-resorptive therapies.
In-vitro, TRAcP 5b activity reflects the number of osteoclasts and therefore the BoneTRAP® (TRAcP 5b) ELISA Assay can be conveniently used to determine osteoclast number in human osteoclast cultures.
Instructions for Use (RUO)
Instructions for Use (RUO)
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