Type
Competitive ELISA
Applications
Serum, Urine, Plasma
Sample Requirements
50 µL
Shipping
At ambient temperature. Upon receipt, store the product at the temperature recommended below.
Storage/Expiration
Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
Calibration Range
15–1000 pg/ml
Limit of Detection
9.1 pg/ml
Intra-assay (Within-Run)
n = 4
CV = 7.7%
Inter-assay (Run-to-Run)
n = 5
CV = 10.8%
Spiking Recovery
106,54%
Dilution Linearity
104,50%
Features
It is intended for research use only.
The kit measures aldosterone levels in serum, plasma and urine.
The total assay time is less than 2.5 hours.
Assay format is 96 wells
Standard is dried aldesterone in a protein-based buffer with a non-mercury preservative. It is prepared by spiking buffer with a defined quantity of aldosterone.
Research topic
Blood pressure regulation and NO metabolism, Bone and cartilage metabolism, Cardiovascular disease, Renal disease, Steroid hormones
Summary
Aldosterone is a potent mineralocorticoid whose synthesis and release are controlled by the renin-angiotensin system of the body. Aldosterone promotes the reabsorption of sodium in the distal tubules of the kidney resulting in potassium secretion along with sodium retention, which controls the circulating blood volume. Chronic overproduction and secretion of aldosterone leads to hypertension.
Instructions for Use (RUO)
Instructions for Use (RUO)
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