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5α-Androstane-3α,17β-diol Glucuronide ELISA

  • Regulatory status:RUO
  • Type:Competitive ELISA, Immobilized antigen
  • Other names:3α Diol G
  • Species:Human
Cat. No. Size Price


RCD007R 96 wells (1 kit) $413,06
PubMed Product Details
Technical Data

Type

Competitive ELISA, Immobilized antigen

Applications

Serum

Sample Requirements

50 μl/well

Shipping

At ambient temperature. Upon receipt, store the product at the temperature recommended below.

Storage/Expiration

Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).

Calibration Curve

Calibration Range

0.25–50 ng/ml

Limit of Detection

0.1 ng/ml

Intra-assay (Within-Run)

CV = 7.0%

Inter-assay (Run-to-Run)

CV = 9.2%

Spiking Recovery

94,40%

Dilution Linearity

93,80%

Summary

Research topic

Steroid hormones

Summary

5α-Androstane-3α, 17β-diol glucuronide is a C19 steroid produced mainly as a metabolite of testosterone and dihydrotestosterone (DHT). It is largely produced in target peripheral tissues such as the skin, especially around hair follicles. The stimulation by large amounts of 3 Diol G leads to excessive hair formation, notably where hair is not normally present in women. Diabetic patients under cyclosporine A therapy have shown increased 3 Diol G levels.

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